Significant additional benefit of mavacamten in hypertrophic obstructive cardiomyopathy

1 February 2024 - In a dossier assessment in 2023, an additional benefit could not yet be proven due to unclear ...

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New orphan drug for a sub-type of acute myeloid leukaemia: G-BA sees significant additional benefit

18 January 2024 - Since July 2023, there has been one in Germany for patients who suffer from acute myeloid leukaemia ...

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Vosoritide in achondroplasia: indication of an additional clinical benefit for children aged two and over

1 December 2023 - Two small RCTs with children of different ages together make it possible to make one statement: the ...

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Early benefit assessment: meaningful RCTs are also feasible in late oncological treatment lines

15 November 2023 - Two randomised controlled studies in the third and fourth lines for colorectal and breast cancer each show ...

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Multiple sclerosis: hardly any evidence for good patient care

4 October 2023 - Even in the final report, many questions about the treatment of relapsing-remitting multiple sclerosis remain unanswered because ...

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Clinical studies: you can see better with the second arm

6 October 2023 - In a statement to the EMA, the IQWiG emphasised that single-arm studies may be sufficient for ...

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Orphan drug for multiple myeloma: G-BA must formally certify legally assumed additional benefit

5 October 2023 - Due to legal requirements, the Federal Joint Committee (G-BA) has completed the re-evaluation process for belantamab mafodotin ...

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How IQWiG assesses – version 7.0 of the method paper comes into force

19 September 2023 - Fundamental revision of the cost benefit assessment and addition of the concept of application-accompanying data collection. ...

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Lisocabtagene maraleucel in second-line B-cell lymphoma: additional benefit for certain patients

1 September 2023 - On the basis of the available data, there is a hint of a non-quantifiable added benefit ...

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Upadacitinib in active Crohn's disease: no additional benefit proven due to a lack of comparative studies

1 August 2023 - Although biologics have been used in Crohn's disease for over 20 years, there are hardly any studies ...

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Access and availability: Why are Europeans finding it hard to get the new medicines they need?

27 July 2023 - Patients are struggling to get hold of the new medicines they desperately need and ask what ...

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"Last hope": Eager Germans are prepared to pay for weight loss drug

25 July 2023 - Frustrated after countless failed diet and exercise attempts, 41 year old Jessica Lenth from Hamburg has ...

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Extension of indications in drug approval: often without proof of additional benefit

6 July 2023 - In a comment in the BMJ, the head of the IQWiG Department for drug assessment advocates approval ...

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EU-HTA: G-BA coordinates parallel scientific consultations for manufacturers from September

3 July 2023 - From 2025, a systematic evaluation of clinical studies for new medicinal products and medical devices will ...

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Planned revision of EU pharmaceutical legislation: early market access and robust evidence need not remain a contradiction in terms

13 June 2023 - On 26 April, the EU Commission presented a proposal for the revision of pharmaceutical legislation in ...

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