Blog
RSS FeedPosted by Michael Wonder on 14 Jun 2018
Effect of cross-over in oncology clinical trials on evidence levels in early benefit assessment in Germany
13 June 2018 - In oncology clinical trials, cross-over is used frequently but may lead to uncertainties regarding treatment effects. ...
Posted by Michael Wonder on 13 Jun 2018
Metastatic breast cancer: highly selective post-hoc analysis rather than complete publication of quality of life data
13 June 2018 - IQWiG employees criticise the publication practice of PALOMA-2 study authors. ...
Posted by Michael Wonder on 16 Jan 2018
Atezolizumab, pembrolizumab, nivolumab in urothelial carcinoma: studies of direct comparison are useful
4 January 2018 - Four dossier assessments involving comparisons between immunotherapies and chemotherapies for the same therapeutic indication in 2017/comparison ...
Posted by Michael Wonder on 15 Jan 2018
German watchdog calls for direct comparison of cancer immunotherapies
16 January 2018 - Germany’s drug assessment body has criticized a lack of data directly comparing drugs in a promising ...
Posted by Michael Wonder on 03 Sep 2017
Nivolumab in squamous cell carcinoma in the head and neck area: additional benefit for certain patients
1 September 2017 - Significant benefit for patients with progression during or shortly after platinum-based therapy. ...
Posted by Michael Wonder on 16 May 2017
Pembrolizumab in non-small-cell lung cancer: a hint of considerable added benefit
15 May 2017 - Patients in the relevant subpopulation of the analysed study survived longer. ...
Posted by Michael Wonder on 29 Mar 2017
German Federal Joint Committee (G-BA) confirms additional benefit of anti-cancer agent Kisplyx (lenvatinib mesylate) in treatment of advanced renal cell carcinoma
28 March 2017 - Eisai announced today that the German Federal Joint Committee (G-BA) has confirmed the additional benefit of in-house ...
Posted by Michael Wonder on 01 Mar 2017
Palbociclib in advanced breast cancer: disadvantages in certain patients
1 March 2017 - More frequent severe side effects in first-line therapy after menopause/missing data for other patients. ...
Posted by Michael Wonder on 06 Jan 2017
German IQWiG confirms additional benefit for Kisplyx (lenvatinib mesylate) in combination with everolimus for the treatment of advanced renal cell carcinoma
4 January 2017 - Approximately 15,000 people in Germany develop renal cell carcinoma every year. ...
Posted by Michael Wonder on 02 Jan 2017
Bronchial carcinoma: additional use of crizotinib not seen
2 January 2017 - The dossier does not contain any suitable data for patients with ROS1 positive non-small-cell lung cancer. ...
Posted by Michael Wonder on 04 Oct 2016
Crizotinib in NSCLC: new data are inconclusive
4 October 2016 - Increased proportion of treatment-change limits further interpretability so the results of the initial IQWiG evaluation shall continue. ...
Posted by Michael Wonder on 04 Oct 2016
Ibrutinib in CLL: no additional clinical benefits for treatment-naïve patients
4 October 2016 - The dossier contains no suitable data on first-line use. ...
Posted by Michael Wonder on 26 Sep 2016
Nivolumab plus ipilimumab in melanoma: added benefit in certain patients
15 September 2016 - Survival advantage in BRAF V600 wild type tumour depends on gender / severe side effects more common. ...
Posted by Michael Wonder on 19 Sep 2016
Talimogene laherparepvec in melanoma: additional clinical benefit not proven
15 September 2016 - Drug manufacturer dossier contained no data suitable for the assessment. ...
Posted by Michael Wonder on 05 Sep 2016
Eisai bewildered as Germany's IQWIG fails to recognise additional benefit of Halaven (eribulin mesylate) in the treatment of advanced liposarcoma
4 September 2016 - Assessment ignores unprecedented overall survival benefit for eribulin in advanced liposarcoma. ...