Statistical and clinical significance

4 September 2017 - In published research, a statistically significant result is often wrongly interpreted as representing a clinically important ...

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Addressing bias and conflict of interest among biomedical researchers

2 May 2017 - Bias in research is ubiquitous and the goal of every researcher should be to reduce bias and ...

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Defining the non-inferiority margin and analysing non-inferiority: an overview

6 March 2017 - Non-inferiority trials are used to assess whether the effect of a new drug is not worse than ...

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Big pharma funding biases drug trials in favour of a sponsor's product: review

21 February 2017 - Drug and device trial studies that are sponsored by the pharmaceutical industry are more likely to ...

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Pharmaceutical industry financial ties linked to 'positive' outcomes in clinical trials for new drugs

18 January 2017 - A new study has found links between medical researchers' financial ties with pharmaceutical companies and "positive" ...

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South Australia to commence PrEP trials

30 November 2016 - The South Australian Premier Jay Wetherill has announced people at high risk of contracting HIV will ...

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Non-inferiority trials: are they inferior? A systematic review of reporting in major medical journals

7 October 2016 -  Academic researchers from the UK have assessed the adequacy of reporting of non-inferiority trials alongside the ...

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Real-world evidence: a comparison of the Australian Herceptin Program and clinical trials of trastuzumab for HER2-positive metastatic breast cancer

19 September 2016 - Estimating the real-world cost-effectiveness of a new drug relies on understanding the differences between clinical trial data ...

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