The fixed-dose combination aclidinium bromide/formoterol has been approved since November 2014 for long-term treatment of adults with chronic obstructive pulmonary disease (COPD). The German Institute for Quality and Efficiency in Health Care (IQWiG) examined in a dossier assessment whether this drug combination offers an added benefit over the appropriate comparator therapy.

According to the findings, there is an indication of minor added benefit for adult patients with moderate COPD (grade II). For adults with grade III and fewer than 2 exacerbations (flare-ups) per year, there is proof of considerable added benefit versus the comparator therapy. In contrast, no conclusions can be drawn on greater or lesser benefit for more severely ill patients from the data presented.

For more details, go to: https://www.iqwig.de/en/press/press-releases/press-releases/aclidinium-bromide/formoterol-in-copd-added-benefit-for-certain-patient-groups.6666.html