Since August 2014, aflibercept (trade name Eylea) has been available also for patients with visual impairment due to diabetic macular oedema (DMO). The German Institute for Quality and Efficiency in Health Care (IQWiG) examined in a dossier assessment whether this drug offers an added benefit over the appropriate comparator therapy.

According to the findings, an added benefit in this therapeutic indication is not proven: The data showed no relevant differences between the treatment groups for patients in whom the fovea centralis is also affected. The drug manufacturer did not submit any data for other patients.

IQWiG already assessed aflibercept twice, in 2013 and in 2014, for therapeutic indications of the eye. In both cases, it concluded that an added benefit is not proven.

For more details, go to: https://www.iqwig.de/en/press/press-releases/press-releases/aflibercept-in-diabetic-macular-oedema-added-benefit-not-proven.6501.html