Clinical equivalence and non-inferiority within health technology assessment

European Journal of Health Economics

23 February 2026 - Non-inferiority and clinical equivalence clinical trials can be used to determine whether a health technology is no worse than an existing treatment. 

This study identified international guidance for conducting non-inferiority and clinical equivalence trials and investigated the current practices in conducting and reporting such trials, especially in the context of health technology assessment.

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Michael Wonder

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Michael Wonder