Conditional power: how likely is trial success?


23 January 2023 - Because of the costs and potential risks to participants, clinical trials should be initiated or continued only when there is a reasonable chance the results will improve clinical care or represent important new knowledge. 

In 2021, McNamee et al. reported the results of a randomised clinical trial evaluating the therapeutic benefit of lower tidal volume ventilation coupled with extracorporeal carbon dioxide removal compared with standard ventilatory support in patients with acute hypoxaemic respiratory failure.

Read JAMA Guide to Statistics and Methods

Michael Wonder

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Michael Wonder

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Clinical trial