COVID-19 vaccines: time to talk about the uncertainties

Nature

20 October 2020 - Plan now for decisions on which vaccines should go to whom, when and how often.

Vaccines will be licensed only after they have been shown to be safe and effective in a general population. This leaves many unknowns: whether one vaccine is more effective than another, how vaccines will work in people who are at the greatest risk of severe illness (people who are often excluded or under-represented in trials), whether vaccines will prevent transmission or severe disease, how long immunity will last — and which groups might resist or reject immunisation because of ideology, mistrust or misinformation.

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Michael Wonder

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Michael Wonder