Posted by Michael Wonder on 24 Aug 2017
Do the American Society of Clinical Oncology Value Framework and the European Society of Medical Oncology Magnitude of Clinical Benefit Scale measure the same construct of clinical benefit?
23 August 2017 - Whether the ASCO Value Framework and the European Society for Medical Oncology Magnitude of Clinical Benefit Scale measure similar constructs of clinical benefit is unclear.
It is also unclear how they relate to quality-adjusted life-years (QALYs) and funding recommendations in the United Kingdom and Canada.
The weak-to-moderate correlations of the ASCO frameworks with the ESMO-MCBS, as well as their correlations with QALYs and with NICE/pCODR funding recommendations, suggest different constructs of clinical benefit measured. Construct convergent validity with the ESMO-MCBS did not increase with the updated ASCO framework.
