Does NICE’s “severity modifier” for assessing diseases need to change?

BMJ

22 November 2024 - Breast cancer charities and patients are “devastated” that the drug Enhertu will not be available in England and Wales after negotiations collapsed over pricing. 

Jacqui Wise examines calls for NICE to rethink its weighting system for evaluating new treatments.

Trastuzumab deruxtecan (Enhertu), made by Daiichi Sankyo and AstraZeneca, is a treatment for adult patients with unresectable or metastatic HER2 low breast cancer who have received previous chemotherapy in the metastatic setting or developed disease recurrence during or within six months of completing adjuvant chemotherapy. In December 2023 the drug was approved for use on the NHS in Scotland after the Scottish Medicines Consortium used its own method to reach its decision.

Read NICE article

Michael Wonder

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Michael Wonder