Posted by Michael Wonder on 04 Apr 2017
Evaluation of evidence of statistical support and corroboration of sub-group claims in randomised clinical trials
3 April 2017 - Many published randomised clinical trials make claims for subgroup differences.
In this meta-epidemiological survey, a minority of sub-group claims (46 of 117) in the abstract of randomised clinical trials were supported by their own data. Only 5 of these 46 sub-group findings had at least 1 subsequent corroboration attempt, and none of the corroboration attempts had a statistically significant P value from an interaction test.
