16 June 2026 - The US FDA today approved another over the counter intranasal naloxone product, Rextovy, a 4 mg naloxone hydrochloride nasal spray for the emergency treatment of opioid overdose.

Consumers may directly purchase this product without a prescription in places such as pharmacies, convenience stores, and online. This action aligns with President Trump’s Great American Recovery Initiative, a federal effort to address the US’ addiction and substance use disorder crisis and coordinate the government's approach to prevention, treatment, and long-term recovery.

Read FDA press release