6 October 2017 - Product label also includes positive data from type 2 diabetes study.

Flexion Therapeutics today announced that the U.S. FDA approved Zilretta (triamcinolone acetonide extended-release injectable suspension), the first and only extended-release, intra-articular injection for osteoarthritis knee pain. Zilretta is a non-opioid medicine that employs Flexion's proprietary microsphere technology to provide proven pain relief over 12 weeks.

"The approval of Zilretta marks a major advancement in the treatment landscape for managing OA knee pain," said Michael Clayman, M.D., President and Chief Executive Officer of Flexion. "It comes at a time when our society is in urgent need of non-addictive therapies to help the millions of Americans who suffer from this condition." Dr. Clayman added, "We believe that Zilretta has the potential to be a transformative medicine for the more than five million patients who receive an intra-articular injection for OA knee pain each year."

The FDA approval of Zilretta is based upon data from Flexion's pivotal Phase 3 clinical trial. The randomised, double-blind study enrolled 484 patients at 37 centers worldwide.

Read Flexion Therapeutics press release