Health Canada approves PrOrkambi (lumacaftor/ivacaftor) - the first medicine to treat the underlying cause of cystic fibrosis for people ages 12 and older with two copies of the F508del mutation
26 January 2016 - Approximately 1,500 people in Canada are ages 12 and older and have two copies of the F508del mutation, the most common genetic form of the disease.