25 May 2023 - Independent appraisal committee narrowly voted that currently available evidence for resmetirom is adequate to demonstrate a net health benefit over lifestyle management, whereas current evidence for obeticholic acid was deemed inadequate to demonstrate a net health benefit.
The ICER today released a final evidence report assessing the comparative clinical effectiveness and value of resmetirom (Madrigal Pharmaceuticals) and obeticholic acid (Ocaliva, Intercept Pharmaceuticals) for non-alcoholic steatohepatitis.