Posted by Michael Wonder on 23 Aug 2018
ICER releases draft evidence report on long-term treatments for prevention of hereditary angioedema attacks
23 August 2018 - Public comment period now open until 20 September; requests to make oral comment during public meeting also being accepted.
The ICER today released a draft evidence report assessing the comparative clinical effectiveness and value of therapies for long-term prophylaxis against hereditary angioedema attacks. Hereditary angioedema is a rare condition characterised by attacks of deep tissue swelling within the skin and/or mucosa.
ICER's report includes four therapies for the prevention of hereditary angioedema attacks: lanadelumab (Shire), which is currently under review by the FDA with an approval decision expected in August 2018, and three C1 inhibitors (Haegarda, CSL Behring; Cinryze, Shire; and Ruconest, Pharming). The report will be subject to deliberation during a public meeting of the California Technology Assessment Forum (CTAF), one of ICER's three independent evidence appraisal committees, in October of 2018.
