9 November 2018 - NICE has issued draft guidelines backing use of Eisai/MSD’s Lenvima on the NHS in England and Wales as an option for a type of untreated, advanced liver cancer.
The Institute has issued a final appraisal document recommending the use of Lenvima (lenvatinib) for untreated, advanced, unresectable hepatocellular carcinoma (HCC) in adults with Child-Pugh grade A liver impairment and an Eastern Cooperative Oncology Group performance status of 0 or 1.
Lenvima, an oral receptor tyrosine kinase inhibitor, is the first new, approved first-line treatment for advanced or unresectable HCC in a decade to show an overall survival treatment effect that was non-inferior to the current standard of care (sorafenib), according to the firm.