Posted by Michael Wonder on 16 Feb 2023
Living health technology assessments: how close to living reality?
16 February 2023 - HTA processes have remained largely unchanged, but innovative study designs (eg, pragmatic and adaptive clinical trials, single-arm trials) are transforming evidence generation, while regulatory decisions are increasingly being based on surrogate endpoints rather than primary outcomes.
This commentary outlines challenges of current, ‘static’ HTA approaches, offers solutions provided by a ‘living’ HTA approach, and considers implementation of this method.
