Posted by Michael Wonder on 08 Mar 2022
NICE draft guidance does not recommend pembrolizumab plus chemotherapy for triple negative breast cancer
8 March 2022 - The evidence showed that pembrolizumab plus chemotherapy is more effective than paclitaxel or nab-paclitaxel, although the long-term benefit is uncertain. In addition, there was no trial data directly comparing pembrolizumab plus chemotherapy with atezolizumab plus chemotherapy, another targeted treatment which NICE already recommends.
Therefore, the cost effectiveness estimates are higher than NICE normally considers an acceptable use of NHS resources.
