NICE has recommended aflibercept solution for injection (Eylea, Bayer) and dexamethasone intravitreal implant (Ozurdex, Allergan) as treatment options for some people with diabetic macular oedema, in two separate pieces of final guidance published today. 

Diabetic macular oedema is a common complication associated with diabetic retinopathyii, and is the most common cause of visual impairment in people with diabetes. It develops when blood vessels in the eye are damaged by a continuously high blood sugar level, causing plasma to leak into the eye. Abnormal new blood vessels also form at the back of the eye (known as the retina). This causes a build-up of excess fluid (oedema) in the macular, which is the central part of the retina. The oedema impairs light perception, causing blurred vision. If it is not treated effectively, it can lead to irreversible vision loss.

The final guidance recommends aflibercept solution for injection as a treatment option in people only if:

• the eye has a central retinal thickness of 400 micrometres or more at the start of treatment, and
• the company provides aflibercept with the discount agreed in the patient access scheme

For more details, go to: http://www.nice.org.uk/news/press-and-media/nice-gives-green-light-to-two-eye-treatments-for-treating-serious-eye-condition