29 November 2016 - Women with a family history of breast cancer should be offered anastrozole, not tamoxifen, says NICE in draft guidance.
NICE recommends new drug to prevent breast cancer in families at high risk.
Women whose close family members have had breast cancer, particularly at an early age may benefit from medicines to reduce their risk of developing the disease.
New evidence demonstrated if 1,000 women at high risk of breast cancer took anastrozole for 5 years 35 cases of breast cancer would be prevented, compared to 21 if they took tamoxifen.
NICE recommends anastrozole is offered for 5 years to women at high risk of breast cancer unless they have severe osteoporosis. And clinicians should consider offering it to women at moderate risk of breast cancer.