Posted by Michael Wonder on 12 Mar 2019
NICE u-turn backs use of Darzalex combo for myeloma relapse
12 March 2019 - Myeloma patients in England are set to gain NHS access to a new second-line treatment combination following a first relapse of the disease.
The National Institute for Health and Care Excellence is now backing NHS use of Janssen’s Darzalex plus Velcade and dexamethasone (DVd) after first relapse of multiple myeloma, having previously turned down the combination in this setting.
According to Janssen, the combination boosts overall survival and slashes the risk of death by 50 percent in this set of patients. However, NICE says the size of the DVd’s benefit in the long-term is “unclear”, because currently available trial relate to a relatively short period of time.
