Pembrolizumab in metastatic NSCLC: now added benefit for subpopulations

IQWiG

19 September 2019 - After a methodological uncertainty has been resolved, analyses on overall survival are now usable

In early July, the German Institute for Quality and Efficiency in Health Care (IQWiG) conducted two early benefit assessments to investigate whether certain drug combinations with pembrolizumab have advantages in comparison with the respective appropriate comparator therapy for patients with metastatic squamous or non-squamous non-small cell lung cancer (NSCLC). 

Due to a contradictory presentation of the operationalization of the key outcome “overall survival” in the drug manufacturer’s dossiers, the presented data were not interpretable, however.

Read IQWiG press release

Michael Wonder

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Michael Wonder