Polivy struck by NICE ‘no’

PM Live

26 February 2020 - The National Institute for Health and Care Excellence has announced that it does not recommend Polivy (polatuzumab), Roche’s treatment for adults with diffuse large B-cell lymphoma.

The organisation has published a draft guidance rejecting the drug in combination with MabThera (rituximab) and bendamustine, for patients whose disease has relapsed or not responded to primary treatment and who cannot have a haematopoietic stem cell transplant.

The decision was made despite clinical trial evidence showing that the cancer became undetectable in around 40% of patients treated with Polivy, MabThera and bendamustine, compared with around 18% of patients treated with MabThera and bendamustine alone.

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Michael Wonder

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Michael Wonder