Sacubitril/valsartan (Entresto) utilisation and prescribing patterns in the context of a reimbursement application system

Br J Clin Pharmacol

12 June 2020 - The aim of this study was to evaluate the utilisation of Entresto in Ireland and compare patient characteristics to those of the pivotal PARADIGM‐HF trial.

In 2018, there were 1043 individuals receiving Entresto, corresponding to an expenditure of €1.2 million. Patients prescribed Entresto in Ireland were older, had lower left ventricular ejection fraction and were more symptomatic than those in the PARADIGM‐HF trial. 

Irish patient characteristics were reflective of Entresto treated populations in other real‐world studies.

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Michael Wonder

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Michael Wonder