Simulating colorectal cancer trials using real world data

JCO Clin Cancer Informatics

20 July 2022 - Using real world data –based trial simulation approach, we aim to simulate colorectal cancer trials and examine both effectiveness and safety end points in different simulation scenarios.

We identified five Phase 3 trials comparing new treatment regimens with an US FDA–approved first-line treatment in patients with metastatic colorectal cancer (ie, fluorouracil, leucovorin, and irinotecan) as the standard care control arm. 

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Michael Wonder

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Michael Wonder