Tezspire approved in the US for chronic rhinosinusitis with nasal polyps

AstraZeneca

17 October 2025 - AstraZeneca and Amgen’s Tezspire (tezepelumab) has been approved in the US for the add-on maintenance treatment of adult and paediatric patients aged 12 years and older with inadequately controlled chronic rhinosinusitis with nasal polyps, a complex epithelial-driven inflammatory condition. 

Tezspire is the first and only biologic that targets thymic stromal lymphopoietin to be approved for chronic rhinosinusitis with nasal polyps.

Read AstraZeneca press release

Read Amgen press release

Michael Wonder

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Michael Wonder

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Outcome , Medicine , US , Registration