11 January 2019 - The EQ-5D instrument is NICE’s preferred measure of health-related quality of life in adults.
The three-level (3L) value set is currently recommended for use, but the five-level (5L) set is increasingly being used in practice. Bennington and colleagues aimed to explore the impact of moving from 3L to 5L in NICE appraisals.
3L and 5L lead to substantially different estimates of incremental QALYs and cost effectiveness. The direction and magnitude of the change is not consistent across case studies.