Upadacitinib monohydrate for the treatment of patients with active non-radiographic axial spondyloarthritis

NICE

1 February 2023 - Upadacitinib monohydrate is recommended as an option for the treatment of adults with active non-radiographic axial spondyloarthritis with objective signs of inflammation (shown by elevated C-reactive protein or MRI) that is not controlled well enough with non-steroidal anti-inflammatory drugs (NSAIDs). 

It is recommended only if:

  • Tumour necrosis factor (TNF) alfa antagonists are not suitable or do not control the condition well enough and
  • AbbVie provides upadacitinib monohydrate according to the commercial arrangement

Read NICE technology appraisal guidance

Michael Wonder

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Michael Wonder