15 July 2022 - The Department of Health and Social Care has asked NICE to produce guidance on using velmanase alfa in the context of national commissioning by NHS England. 

The highly specialised technologies evaluation committee has considered the evidence submitted by Chiesi and the views of non-company consultees and commentators, clinical experts, patient experts and NHS England.

Velmanase alfa is not recommended for treating the non-neurological signs and symptoms of mild to moderate alfa mannosidosis.

Read NICE evaluation consultation document