Vertex announces marketing authorisation in Canada for Alyftrek, a once daily next generation CFTR modulator for the treatment of cystic fibrosis

Vertex Pharmaceuticals

22 July 2025 - Approximately 3,800 people in Canada are now eligible for Alyftrek, with up to 60 people potentially eligible for a medicine that treats the underlying cause of their disease for the first time.

Vertex Pharmaceuticals today announced that Health Canada has granted marketing authorisation for Alyftrek (vanzacaftor/tezacaftor/deutivacaftor), a new triple combination therapy for patients living with cystic fibrosis ages 6 years and older who have at least one F508del mutation or another responsive mutation in the cystic fibrosis transmembrane conductance regulator gene.

Read Vertex Pharmaceuticals press release

Michael Wonder

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Michael Wonder