Vildagliptin (trade name Galvus or Jalra) has been approved since September 2007 for adults with type 2 diabetes mellitus in whom diet and exercise do not provide adequate glycaemic control. The German Institute for Quality and Efficiency in Health Care (IQWiG) examined in a new dossier assessment whether this drug offers an added benefit over the appropriate comparator therapy. Such an added benefit cannot be derived from the new dossier either, however, because the drug manufacturer did not submit any suitable data.

Neither the first dossier assessment from July 2013 nor the assessment of the manufacturer’s data subsequently submitted from October 2013 resulted in an advantage of vildagliptin for any of the possible therapeutic indications. Referring to results of one further study, which have become available in the meantime, the manufacturer applied to the Federal Joint Committee (G-BA) for a new dossier assessment for the combination with a sulfonylurea.

For more details, go to: https://www.iqwig.de/en/press/press-releases/press-releases/vildagliptin-for-type-2-diabetes-no-suitable-data-for-combination-with-sulfonylurea.6608.html