Blog
RSS FeedPosted by Michael Wonder on 04 Apr 2024
New model validation tool to support economic evaluations of health technologies
1 April 2024 - CADTH has developed a comprehensive and accessible tool to support the validation of economic models used in ...
Posted by Michael Wonder on 29 Nov 2022
FDA looks to modelling and simulation tools to streamline product reviews
28 November 2022 - The US FDA recently published a report on how it uses modelling and simulation, highlighting the untapped ...
Posted by Michael Wonder on 10 Nov 2020
ICER provides second update to pricing models for remdesivir as a treatment for COVID-19
10 November 2020 - Based on an analysis of four studies evaluating remdesivir’s influence on mortality, ICER has concluded that the ...
Posted by Michael Wonder on 10 Oct 2020
In landmark international program, HTA agencies around the world access ICER's customisable COVID-19 cost-effectiveness model
9 October 2020 - Leveraging ICER’s new cloud-based Interactive Modeler platform, Quebec’s HTA agency has used the COVID-19 model to inform ...
Posted by Michael Wonder on 05 Jul 2020
Assessment of technical errors and validation processes in economic models submitted by the company for NICE technology appraisals
3 July 2020 - Economic models play a central role in the decision-making process of NICE. ...
Posted by Michael Wonder on 28 May 2020
Nonparametric statistical analysis
26 May 2020 - Many statistical methods start with a statistical assumption that the distribution of measured values can be summarised ...
Posted by Michael Wonder on 28 May 2020
Modelling epidemics with compartmental models
27 May 2020 - During epidemics, there is a critical need to understand both the likely number of infections and their ...
Posted by Michael Wonder on 22 Apr 2020
Prediction models - development, evaluation and clinical application
23 April 2020 - When national lipid guidelines first incorporated a model based on data from the Framingham Heart Study — ...
Posted by Michael Wonder on 18 Nov 2019
Improving transparency in decision models: current issues and potential solutions
23 October 2019 - Decision-analytic models have become an essential tool used to inform health technology assessments. ...
Posted by Michael Wonder on 30 Oct 2019
Model assisted designs for early phase clinical trials: simplicity meets superiority
30 October 2019 - Drug development enterprise is struggling because of prohibitively high costs and slow progress. ...
Posted by Michael Wonder on 09 Sep 2019
Achieving appropriate model transparency: challenges and potential solutions for making value‑based decisions in the United States
5 September 2019 - Transparency in decision modeling remains a topic of rigorous debate among healthcare stakeholders, given tensions between the ...
Posted by Michael Wonder on 09 Mar 2019
Marginal effects—quantifying the effect of changes in risk factors in logistic regression models
8 March 2019 - Marginal effects can be used to express how the predicted probability of a binary outcome changes ...
Posted by Michael Wonder on 22 Feb 2019
Choosing a time horizon in cost and cost-effectiveness analyses
21 February 2019 - When designing a comparative outcomes or a cost-effectiveness analysis, the time horizon defining the duration of time ...
Posted by Michael Wonder on 20 Oct 2018
Is the EUnetHTA HTA core model fit for purpose? Evaluation from an industry perspective
18 October 2018 - The HTA Core Model was developed to improve the transferability of health technology assessment between settings. ...
Posted by Michael Wonder on 16 Oct 2018
Model structuring for economic evaluations of new health technologies
17 October 2018 - In countries such as Australia, the UK and Canada, decisions on whether to fund new health technologies ...