Pertuzumab and pertuzumab with trastuzumab in breast cancer: now a minor additional clinical benefit

2 January 2023 - Advantages in overall survival and in relapses often only become apparent after a long period of ...

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COVID-19: nirmatrelvir/ritonavir reduces the risk of a severe course in patients at risk

4 October 2022 - However, due to contra-indications and interactions, the combination of active ingredients is not suitable for all patients ...

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Palbociclib combination in advanced breast cancer: again only disadvantages

5 October 2022 - For post-menopausal women with hormone receptor positive, HER2 negative breast cancer in the first line, there is ...

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Advanced oesophageal carcinoma: nivolumab in combination with chemotherapy or ipilimumab prolongs life compared to chemotherapy alone

1 August 2022 - The additional clinical benefit cannot be quantified because the data on health status and health-related quality ...

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Post-menopausal osteoporosis: advantages of teriparatide over risedronate sodium

2 June 2022 - Preliminary report on the comparative benefit assessment of bisphosphonates, teriparatide and denosumab is available. Please submit ...

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G-BA certifies active ingredients against breast and oesophageal cancer as having a high additional benefit

19 May 2022 - The Federal Joint Committee (G-BA) has rated the patient-relevant additional benefit of two active ingredients for cancer ...

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Lenvatinib and pembrolizumab in endometrial cancer: patients live significantly longer

19 April 2022 - There is an indication of a considerable added benefit compared to doxorubicin or paclitaxel. Compared to ...

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Triple negative breast cancer: survival benefit with sacituzumab govitecan

1 March 2022 - Those affected survive a median of twelve months compared to seven in the control group. Overall, ...

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Hyposensitisation with AR101 in peanut allergy: proof of lesser benefit

17 January 2022 - In the patient-relevant outcomes, there are only disadvantages for 4- to 17-year-olds compared to a pure peanut-avoiding ...

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Daratumumab in multiple myeloma: reassessment results in hint of considerable added benefit

3 January 2022 - Janssen applied for a new early benefit assessment due to new scientific findings.  ...

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Nivolumab for the adjuvant treatment of oesophageal carcinoma: indication of minor added benefit

1 December 2021 - Those affected develop fewer relapses than if they wait and see.  ...

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Upadacitinib in atopic dermatitis: additional benefit for adults at high dose

1 December 2021 - Women should expect more serious adverse effects than men.  ...

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Nivolumab and ipilimumab: added benefit in pleural mesothelioma with non-epithelioid tumour histology

1 October 2021 - For the first time, a pure antibody combination has been approved as a first-line therapy for ...

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Adjuvant treatment for NSCLC: osimertinib mesylate may benefit certain people

1 October 2021 - Hint of considerable additional benefit if, after complete tumour resection, adjuvant platinum-based chemotherapy has already been ...

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With remdesivir, the Federal Joint Committee assesses the additional benefit of an anti-viral COVID-19 drug for the first time

16 September 2021 - Do patients with COVID-19 have a better chance of surviving and recovering faster if they are treated ...

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