Real-world evidence to support health technology assessment and payer decision making: is it now or never?

31 March 2025 - The aim of this policy article is twofold: (i) to provide a summary and update of recent ...

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Efanesoctocog alfa for the treatment and prevention of bleeding episodes in patients with haemophilia A (final guidance)

2 April 2025 - NICE has published final evidence-based recommendations on the use of efanesoctocog alfa (Altuvoct) for the treatment ...

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Pembrolizumab in combination with carboplatin and paclitaxel for the treatment of patients with advanced or recurrent endometrial cancer

24 March 2025 - The Department of Health and Social Care has asked NICE to produce guidance on the use ...

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Nemolizumab for the treatment of patients with moderate to severe atopic dermatitis

27 March 2025 - The Department of Health and Social Care has asked NICE to produce guidance on the use ...

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First licensed treatment for ultra-rare immune disorder recommended

13 March 2025 - Leniolisib is the first ever treatment for activated phosphoinositide 3-kinase delta syndrome licensed for use in the ...

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First daily pill for endometriosis approved for NHS use

13 March 2025 - Today we've recommended the first long-term daily pill to treat endometriosis that could transform how this painful ...

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Atezolizumab for the first-line treatment of adults with advanced or recurrent non-small-cell lung cancer when platinum-doublet chemotherapy is unsuitable

12 March 2025 - NICE is unable to make a recommendation on the use of atezolizumab (Tecentriq) in the NHS for ...

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Zolbetuximab in combination with chemotherapy for the first-line treatment of adults with claudin-18.2 positive, HER2 negative unresectable advanced gastric or gastro-oesophageal junction adenocarcinoma (final guidance)

12 March 2025 - NICE has published final evidence-based recommendations on the use of zolbetuximab (Vyloy) in combination with chemotherapy ...

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Natalizumab for the treatment of patients with highly active relapsing–remitting multiple sclerosis after disease-modifying therapy

12 March 2025 - The Department of Health and Social Care has asked NICE to produce guidance on the use ...

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Amivantamab in combination with pemetrexed disodium heptahydrate and carboplatin for the treatment of patients with advanced EGFR exon 20 insertion mutation positive non-small-cell lung cancer

6 March 2025 - The Department of Health and Social Care has asked NICE to produce guidance on the use ...

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Second consultation launched on NHS funding for Alzheimer's treatments

6 March 2025 - Cost and evidence gaps remain barriers to approving funding in the NHS for donanemab and lecanemab. ...

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Cemiplimab in combination with platinum-based chemotherapy for the treatment of patients with advanced non-small-cell lung cancer

5 March 2025 - The Department of Health and Social Care has asked the NICE to produce guidance on the ...

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Idebenone for the treatment of patients 12 years of age and older with visual impairment in Leber’s hereditary optic neuropathy (updated draft guidance)

5 March 2025 - NICE has produced additional draft guidance on the use of idebenone in the NHS in England. ...

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Sparsentan for the treatment of patients with primary IgA nephropathy

4 March 2025 - The Department of Health and Social Care has asked NICE to produce guidance on the use ...

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Exagamglogene autotemcel for the treatment of patients with severe sickle cell disease

26 February 2025 - NICE has published final evidence-based recommendations on the use of exagamglogene autotemcel (Casgevy) for the treatment ...

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