Blog
RSS FeedPosted by Michael Wonder on 21 Feb 2025
Use of surrogate endpoints in health technology assessment: a review of selected NICE technology appraisals in oncology
19 February 2025 - Surrogate endpoints, used to substitute for and predict final clinical outcomes, are increasingly being used to support ...
Posted by Michael Wonder on 17 Jan 2025
International collaboration provides new guidance on the use of surrogate outcomes in cost effectiveness analysis
17 January 2025 - Recommendations will help organisations that evaluate new drugs establish whether their use will result in longer-term benefits ...
Posted by Michael Wonder on 13 Apr 2023
How ‘surrogate outcomes’ influence long-term health outcomes
13 April 2023 - NICE working with international organisations to develop guidance. ...
Posted by Michael Wonder on 11 Jul 2018
Challenges and methodologies in using progression free survival as a surrogate for overall survival in oncology
11 July 2018 - A primary outcome in oncology trials is overall survival. However, to estimate overall survival accurately requires ...
Posted by Michael Wonder on 22 Mar 2017
The role of imperfect surrogate endpoint information in drug approval and reimbursement decisions
22 March 2017 - Weakly correlated surrogates encourage payers and regulators to impose more stringent evidence thresholds. ...