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RSS FeedPosted by Michael Wonder on 13 Apr 2023
How ‘surrogate outcomes’ influence long-term health outcomes
13 April 2023 - NICE working with international organisations to develop guidance. ...
Posted by Michael Wonder on 11 Jul 2018
Challenges and methodologies in using progression free survival as a surrogate for overall survival in oncology
11 July 2018 - A primary outcome in oncology trials is overall survival. However, to estimate overall survival accurately requires ...
Posted by Michael Wonder on 22 Mar 2017
The role of imperfect surrogate endpoint information in drug approval and reimbursement decisions
22 March 2017 - Weakly correlated surrogates encourage payers and regulators to impose more stringent evidence thresholds. ...