Predictive validation and the re-analysis of cost-effectiveness: do we dare to tread?

30 October 2017 - Predictive validation (also known as fourth-order validation) involves the comparison between model outputs and observed data ...

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In search of a common currency: a comparison of seven EQ-5D-5L value sets

24 October 2017 - The recently published EQ-5D-5L value sets from Canada, England, Japan, Korea, the Netherlands, Spain, and Uruguay are ...

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Exploration and preferential ranking of patient benefits of medical devices: a new and generic instrument for health economic assessments

25 October 2017 - For medical devices, benefits other than direct clinical effects may have a large impact on the patients’ ...

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Taking patient heterogeneity and preferences into account in health technology assessments

25 October 2017 - The INTEGRATE-HTA project provided methodology to evaluate complex technologies.  ...

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Can ad hoc analyses of clinical trials help personalise treatment decisions?

23 October 2017 - The value of ad hoc analyses of clinical trials may not be clear. Ad hoc analyses are ...

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NICE bars NHS access to Lenvima, Nexavar for thyroid cancer

23 October 2017 - NHS treatment cost regulators have published draft guidelines rejecting funding for Eisai’s Lenvima and Bayer’s Nexavar ...

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GSK wins U.S. shingles vaccine approval, UK nod for gene therapy

23 October 2017 - GlaxoSmithKline has won U.S. approval for a new and improved shingles vaccine, the second of three ...

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NICE approves gene therapy for rare ‘bubble baby syndrome’

23 October 2017 - Strimvelis, a treatment for an ultra-rare inherited immune deficiency condition that has been dubbed ‘bubble baby syndrome’ ...

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NHS to fund gene therapy for 'bubble babies'

23 October 2017 - The NHS will fund gene therapy for the first time, with a £500,000 treatment for “bubble ...

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Taxpayer-funded drugs 'too expensive for patients’

22 October 2017 - Taxpayer-funded medical research is producing medicines which are increasingly unaffordable for patients who need them, says ...

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National PreP service would be cost effective, research finds

20 October 2017 - Providing pre-exposure prophylaxis treatment to men who have sex with men at high risk of contracting ...

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NICE no for Opdivo in urothelial carcinoma

20 October 2017 - The National Institute for Health and Care Excellence has published draft guidelines rejecting NHS funding for ...

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Economic evaluation of personalised medicine: a call for real-world data

18 October 2017 - In the last decade, we have witnessed a change in healthcare management, with ‘personalised medicine’ as the ...

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‘No-deal’ Brexit could cost NHS £500m a year

17 October 2017 - A ‘no-deal’ Brexit that ends healthcare arrangements between the UK and the EU could end up ...

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Roche’s skin cancer drug Erivedge pulled from CDF

13 October 2017 - Roche’s Erivedge could be removed from the Cancer Drugs Fund within months after the National Institute ...

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