Dostarlimab with platinum-based chemotherapy for treating primary advanced or recurrent endometrial cancer with high microsatellite instability or mismatch repair deficiency

22 May 2025 - Dostarlimab, when used in combination with platinum-based chemotherapy, can be used as an option for the ...

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Erdafitinib for the treatment of patients with unresectable or metastatic urothelial cancer with an FGFR3 alteration after a PD-1 or PD-L1 inhibitor

12 May 2025 - Erdafitinib is recommended as an option for the treatment of adults with unresectable or metastatic urothelial cancer ...

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Adagrasib for previously treated patients with advanced KRAS G12C mutation positive non-small-cell lung cancer

9 May 2025 - The Department of Health and Social Care has asked NICE to produce guidance on the use ...

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Osimertinib mesylate in combination with pemetrexed disodium heptahydrate and platinum-based chemotherapy for patients with advanced EGFR mutation positive non-small-cell lung cancer (final guidance)

8 May 2025 - Osimertinib mesylate, when used in combination with pemetrexed disodium heptahydrate and platinum-based chemotherapy, is recommended as an ...

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Thousands of people a year could benefit from new twice a day tablet for advanced breast cancer

11 April 2025 - We've published final draft guidance recommending capivasertib with fulvestrant, which means the treatment will be funded immediately ...

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Hundreds of people in England to benefit from take-at-home tablet bladder cancer treatment

10 April 2025 - Today, for the first time, we have given the green light to a targeted treatment for the ...

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Lorlatinib for the treatment of patients with advanced ALK positive non-small-cell lung cancer (review of TA909)

9 April 2025 - The Department of Health and Social Care has asked NICE to produce guidance on the use ...

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Pembrolizumab in combination with carboplatin and paclitaxel for the treatment of patients with advanced or recurrent endometrial cancer

24 March 2025 - The Department of Health and Social Care has asked NICE to produce guidance on the use ...

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Atezolizumab for the first-line treatment of adults with advanced or recurrent non-small-cell lung cancer when platinum-doublet chemotherapy is unsuitable

12 March 2025 - NICE is unable to make a recommendation on the use of atezolizumab (Tecentriq) in the NHS for ...

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Zolbetuximab in combination with chemotherapy for the first-line treatment of adults with claudin-18.2 positive, HER2 negative unresectable advanced gastric or gastro-oesophageal junction adenocarcinoma (final guidance)

12 March 2025 - NICE has published final evidence-based recommendations on the use of zolbetuximab (Vyloy) in combination with chemotherapy ...

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Amivantamab in combination with pemetrexed disodium heptahydrate and carboplatin for the treatment of patients with advanced EGFR exon 20 insertion mutation positive non-small-cell lung cancer

6 March 2025 - The Department of Health and Social Care has asked NICE to produce guidance on the use ...

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Cemiplimab in combination with platinum-based chemotherapy for the treatment of patients with advanced non-small-cell lung cancer

5 March 2025 - The Department of Health and Social Care has asked the NICE to produce guidance on the ...

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Osimertinib mesylate for the adjuvant treatment of patients with EGFR mutation positive non-small-cell lung cancer after complete tumour resection (final guidance)

26 February 2025 - NICE has published final evidence-based recommendations on the use of osimertinib mesylate (Tagrisso) for the adjuvant ...

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Green light for groundbreaking personalised cancer therapy that reprogrammes immune system

20 February 2025 - Final guidance published today recommends lisocabtagene maraleucel (Breyanzi; Bristol Myers Squibb) as an option for treating ...

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Use of surrogate endpoints in health technology assessment: a review of selected NICE technology appraisals in oncology

19 February 2025 - Surrogate endpoints, used to substitute for and predict final clinical outcomes, are increasingly being used to support ...

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