Blog
RSS FeedPosted by Michael Wonder on 29 Nov 2022
FDA looks to modelling and simulation tools to streamline product reviews
28 November 2022 - The US FDA recently published a report on how it uses modelling and simulation, highlighting the untapped ...
Posted by Michael Wonder on 28 May 2020
Nonparametric statistical analysis
26 May 2020 - Many statistical methods start with a statistical assumption that the distribution of measured values can be summarised ...
Posted by Michael Wonder on 28 May 2020
Modelling epidemics with compartmental models
27 May 2020 - During epidemics, there is a critical need to understand both the likely number of infections and their ...
Posted by Michael Wonder on 22 Apr 2020
Prediction models - development, evaluation and clinical application
23 April 2020 - When national lipid guidelines first incorporated a model based on data from the Framingham Heart Study — ...
Posted by Michael Wonder on 30 Oct 2019
Model assisted designs for early phase clinical trials: simplicity meets superiority
30 October 2019 - Drug development enterprise is struggling because of prohibitively high costs and slow progress. ...
Posted by Michael Wonder on 09 Mar 2019
Marginal effects—quantifying the effect of changes in risk factors in logistic regression models
8 March 2019 - Marginal effects can be used to express how the predicted probability of a binary outcome changes ...
Posted by Michael Wonder on 14 Mar 2017
Logistic regression diagnostics: understanding how well a model predicts outcomes
14 March 2017 - In the 8 March 2016, issue of JAMA, Zemek et al used logistic regression to develop ...
Posted by Michael Wonder on 14 Nov 2016
Modelling and simulation in the development of medicines
14 November 2016 - Watch live broadcast of expert discussion at EMA. ...
Posted by Michael Wonder on 31 Jul 2016
Modelling and simulation in the development and regulatory review of medicines
29 July 2016 - Comments on new guidance invited until 31 January 2017. ...