Estimands, estimators and estimates


23 August 2021 - The primary goal of most randomised clinical trials is to draw conclusions about the effect of a treatment in a specific population of patients. 

The true effect of the intervention, termed the estimand, is estimated with the data acquired in the trial, subject to limitations associated with variations in adherence to treatment, patients being lost to follow-up, and data quality.

Read JAMA Guide to Statistics and Methods

Michael Wonder

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Michael Wonder

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Medicine , US , Regulation , Statistics