Incidental imaging findings in clinical trials

JAMA

13 January 2020 - Clinical trial end points are outcome measures used to assess the efficacy and safety of an intervention. 

The selection of end points is based on their perceived clinical importance and accuracy of measurement. If correctly defined and collected, these outcome variables enable the translation of clinical trial data into evidence-based recommendations. 

Yet as technology changes and clinical practices evolve, emerging clinical events that are unrelated to the study intervention may be missed when conventional end points are used.

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Michael Wonder

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Michael Wonder

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US , Clinical trial , Research