The value of using registries to evaluate randomised clinical trial study populations

JAMA Internal Medicine

5 June 2017 - Randomised clinical trials are considered the gold standard of medical research and influence clinical practice, but they do not address all relevant clinical questions.

The study designs used in randomised clinical trials have many benefits, and are clearly the best way to limit bias and confounding. However, they may only apply to the study population at issue and cannot be assumed to translate to other patient populations.

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Michael Wonder

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Michael Wonder

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Clinical trial , Bias