23 November 2021 - The goal of much of medical research is to determine which of 2 or more therapeutic approaches is most effective in a given situation.
The power of a study is the probability of detecting a true treatment effect of a given magnitude and is highly dependent on the number of patients studied. When a retrospective observational study design is used, researchers have little or no control over the sample size, and thus little control over the power to detect a particular treatment effect.