Vertex announces Casgevy reimbursement agreement for the treatment of transfusion-dependent beta thalassaemia and sickle cell disease in Italy

Vertex Pharmaceuticals

18 September 2025 - Italy has the largest population of people living with transfusion-dependent beta thalassaemia in Europe.

Vertex Pharmaceuticals announced today a reimbursement agreement with the Italian Medicines Agency for eligible transfusion-dependent beta thalassaemia and severe sickle cell disease patients to access the CRISPR/Cas9 gene-edited therapy, Casgevy (exagamglogene autotemcel).

Read Vertex Pharmaceuticals press release

Michael Wonder

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Michael Wonder