Upadacitinib in active Crohn's disease: no additional benefit proven due to a lack of comparative studies

1 August 2023 - Although biologics have been used in Crohn's disease for over 20 years, there are hardly any studies ...

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"Last hope": Eager Germans are prepared to pay for weight loss drug

25 July 2023 - Frustrated after countless failed diet and exercise attempts, 41 year old Jessica Lenth from Hamburg has ...

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Extension of indications in drug approval: often without proof of additional benefit

6 July 2023 - In a comment in the BMJ, the head of the IQWiG Department for drug assessment advocates approval ...

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Orphan drugs: early generation of evidence urgently needed

10 May 2023 - A team led by IQWiG authors, together with Rita Banzi from the Italian Mario Negri Institute, analysed ...

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Olaparib in metastatic prostate cancer: added benefit for certain patients

17 April 2023 - Younger treatment naïve patients benefit. No relevant data were presented for previously treated patients. ...

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Are German drug pricing regulations chasing some drug makers away, causing them to withdraw products from the market?

5 April 2023 - Germany’s pharmaceutical market is the most important one on the European continent.  ...

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Zanubrutinib in chronic lymphocytic leukaemia: additional benefit for certain patients

15 March 2023 - For adults with relapsed/refractory chronic lymphocytic leukaemia who have not yet received a BTK or BCL2 inhibitor, ...

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Efficient RCTs with real world data for benefit assessments: accelerating evidence-based care

2 March 2023 - Together with colleagues from the Belgian HTA agency KCE, three employees of IQWiG in the BMJ are ...

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Thomas Kaiser becomes the new head of IQWiG

16 February 2023 - The current head of the IQWiG department for drug assessment succeeds Jürgen Windeler, who is retiring after ...

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Germany proposes to fix shortages in certain medicines

15 February 2023 - Germany's health ministry on Tuesday vowed to fix shortages in medicines for children, antibiotics and cancer ...

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Advanced breast cancer: now a significant added benefit for trastuzumab deruxtecan

2 February 2023 - New results from an early-initiated study show advantages in overall survival. ...

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Draft methods (version 7.0): IQWiG is extending the comment period

26 January 2023 - The new deadline is 28 February 2023. ...

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Vutrisiran in hereditary transthyretin amyloidosis: hint of minor added benefit

17 January 2023 - Vutrisiran is approved for the treatment of patients with hereditary transthyretin amyloidosis with stage 1 or ...

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Pertuzumab and pertuzumab with trastuzumab in breast cancer: now a minor additional clinical benefit

2 January 2023 - Advantages in overall survival and in relapses often only become apparent after a long period of ...

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Meta-analyses with very few studies: different beta-binomial models in comparison

16 December 2022 - A team led by IQWiG authors compared the usual beta-binomial model for meta-analysis of small study pools ...

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